Extensive nuclear reprogramming and endoreduplication in mature leaf during floral induction
نویسندگان
چکیده
منابع مشابه
Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional.
An understanding of nuclear reprogramming is fundamental to the use of cells in regenerative medicine. Due to technological obstacles, the time course and extent of reprogramming of cells following fusion has not been assessed to date. Here, we show that hundreds of genes are activated or repressed within hours of fusion of human keratinocytes and mouse muscle cells in heterokaryons, and extens...
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Somatic cell nuclear transfer (SCNT or cloning) returns a differentiated cell to a totipotent status; a process termed nuclear reprogramming. Reproductive cloning has potential applications in both agriculture and biomedicine, but is limited by low efficiency. To understand the deficiencies of nuclear reprogramming, our research has focused on both candidate genes and global gene expression pat...
متن کاملReprogramming somatic cells: pluripotency through gene induction and nuclear transfer
Background: The understanding of nuclear reprogramming pathways provides important contributions to applied and basic sciences such as the development of autologous cellular therapies for the treatment of numerous diseases, the improved efficiency of animal-based biotechnology or the generation of functional gametes in vitro. Strategies such as nuclear transfer and induced reprogramming have be...
متن کاملFloral Induction and Florigen
that they are not sensitive to environmental cues. The Milo J. Aukerman and Rick M. Amasino Department of Biochemistry extent to which environmental-response pathways versus autonomous pathways control flowering varies 420 Henry Mall University of Wisconsin among plant species. Even within a species there are often photoperiod-responsive and -nonresponsive types Madison, Wisconsin 53706-1569 th...
متن کاملNuclear reprogramming.
There is currently particular interest in the field of nuclear reprogramming, a process by which the identity of specialised cells may be changed, typically to an embryonic-like state. Reprogramming procedures provide insight into many mechanisms of fundamental cell biology and have several promising applications, most notably in healthcare through the development of human disease models and pa...
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ژورنال
عنوان ژورنال: BMC Plant Biology
سال: 2019
ISSN: 1471-2229
DOI: 10.1186/s12870-019-1738-6